Exam questions

While anatomy is about structure, physiology is about function. Thus, most of the exam questions will expect you to describe and explain some action, function. You should be able to answer not only a question How, but also Why.

Official, currently valid version of exam questions is in the Study information system (SIS); here is a copy:

 

PHYSIOLOGY EXAM QUESTIONS 

1. Osmosis, diffusion, oncotic pressure

2. Causes of uneven distribution of ions on the two sides of plasma membrane

3. Transport of substances across plasma membrane

4. Body fluids compartments. Composition and measurement.

5. Generation of action potentials

6. Muscle contraction mechanics. isotonic and isometric contraction.

7. Contraction of smooth muscle

8. Action potentials in the heart

9. Pacemaker cells in the heart. Heart rate regulation.

10. ECG curve and its measurement

11. Cardiac and skeletal muscle contraction comparison

12. Excitation-contraction coupling in cardiac and skeletal muscles

13. Autoregulation of myocardial contraction (homeometric, heterometric)

14. Cardiac cycle: meaning of all parts of the PV loop

15. Cardiac output

16. Relation between blood pressure and blood flow

17. Blood pressure regulation

18. Long-term regulation of blood pressure by the kidneys

19. Neural regulation of cardiac output distribution

20. Local regulation of blood flow (metabolic, myogenic)

21. Coronary blood flow

22. Circulatory system response to physical exercise

23. Tissue fluid, circulation of lymph, regional differences in production of tissue fluid, Starling equation, capillary equilibrium

24. Factors determining composition of alveolar air and arterial blood. Effect of dead space.

25. Respiration mechanics. Respiratory muscles.

26. Factors determining lung compliance and airway resistance.

27. Respiratory work

28. Factors affecting ventilation/perfusion ratio. Consequences.

29. Diffusion of O2 and CO2 across the alveolar-capillary membrane. Limits of perfusion and diffusion.

30. Oxygen-haemoglobin dissociation curve

31. Transport of gasses by blood and factors affecting it

32. Chemical regulation of breathing

33. Neural regulation of breathing

34. Functional differences between systemic and pulmonary circulation

35. Types of hypoxia

36. Spirometry: principle of measurement. Static and dynamic parameters of the lungs

37. Renal blood flow. Its regulation and relationship to glomerular filtration.

38. Factors determining glomerular filtration

39. Glomerular filtration measurement. Renal blood flow measurement.

40. Tubular transport measurement

41. Proximal tubule transport mechanisms

42. Renin-angiotensin-aldosterone system

43. Renal secretion of potassium

44. Renal secretion of urea. Ammonia metabolism in renal tubules.

45. Creation of concentrated and diluted urine. Regulation of water intake.

46. Kidney role in acid-base balance

47. Factors determining acid-base balance

48. Skeletal muscle tone regulation. Gamma system.

49. Contraction of skeletal muscles.

50. Red blood cells. Erythropoiesis, function, and ontogenesis.

51. Blood types. Rh incompatibility between the baby's and mother's blood.

52. Haemostasis and hemocoagulation. Factors.

53. Swallowing: oesophageal motility, secretion of saliva, regulation

54. Regulation of gastric motility

55. Regulation of intestinal motility - small intestine

56. Regulation of intestinal motility - large intestine. Defecation.

57. Regulation of gastric juice secretion

58. Regulation of pancreatic juice secretion

59. Bile

60. Regulation of intestinal juice secretion

61. Digestion and absorption of water, nutrients, ions, and vitamins

62. Metabolism of iron, phosphates, and calcium. Calcemia regulation.

63. Thermoregulation. Heat loss. Ontogenesis of thermoregulation.

64. Function of hormones

65. Pituitary hormones and their importance for the development of an individual.

66. Thyroid gland function

67. Glucocorticoids

68. Adrenocorticoids

69. Endocrine function of the testes

70. Endocrine function of the ovaries. Menstrual cycle.

71. Endocrine function of the adipose tissue

72. Hormonal changes during pregnancy. Placenta. Delivery.

73. Changes in circulatory and respiratory systems at birth

74. Hormones and trophic changes during postnatal ontogenesis

75. Endocrine function of the pancreas. Regulation of glycemia. Clinical measurement. 

76. Neuronal action potential. Function of myelin sheath.

77. Axon conductivity and nerve fibre typology

78. Neurotransmission. Metabotropic and ionotropic receptors.

79. Excitatory neurotransmitter systems

80. Inhibitory neurotransmitter systems

81. Blood-brain barrier. Glia cells. Extracellular milieu.

82. Brain ventricles. Cerebrospinal fluid: generation, composition, importance. Intracranial pressure.

83. Cerebral blood flow. Its regulation and metabolism of neurones.

84. Reflexes: mechanism and classification.

85. Spinal cord function

86. Voluntary control of movement

87. Role of basal ganglia in motor control

88. Role of the cerebellum in motor control

89. Regulation of gait and balance

90. Autonomic nervous system

91. EEG and evoked potentials

92. Reticular formation of the brainstem. Modulatory systems.

93. Sleep and wakefulness

94. Limbic system. Motivation and emotion.

95. Forms of memory

96. Memory trace formation

97. Speech and its disorders

98. Eye

99. Function of the retina

100. Ear. Auditory transduction.

101. Statokinetic system. Nystagmus.

102. Olfactory and gustatory systems

103. Somatosensory system, proprioception, pain

Created: 15. 9. 2021 / Modified: 18. 9. 2021 / Responsible person: prof. RNDr. Václav Hampl, DrSc.